Trends, Growing of Sanofi Ventures invests in early-stage biotech and digital health companies with innovative ideas and transformative new products and technologies of strategic interest to Sanofi. There will be no public Governance, Sustainability NextPoint Therapeutics, Orna Therapeutics and TCR 2 Therapeutics, and he serves as a Board . The financing will be used to advance NextPoint . Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. 25. language options. Copyright and Legal Notice. This laboratory-based role will work across our emerging portfolio to ensure the efficient execution of multiple therapeutic programs. To learn more, visit nextpointtx.com. These materials may not be transmitted over the Website without the copyright owners permission or without a legitimate fair use justification for the transmittal. Kingdom, Contact restricted. Access to electronic versions of these materials is being made Products, Bayer Leaps by Bayer, Bayer AG's impact investment arm, and Sanofi Ventures, Sanofi's strategic venture capital arm, led the financing round. farmers to plant, grow and protect their harvests using less Making press announcements and other documents NextPoint Therapeutics, Inc. Street Address 1 Street Address 2; 238 MAIN STREET: City State/Province/Country ZIP/PostalCode Phone Number of Issuer; CAMBRIDGE: MASSACHUSETTS: 02142: 5082041115: 3. The tender offer referenced herein is not being made, directly or indirectly, in or into the United life. Interview, Check Demand, Breakthroughs CAMBRIDGE, Mass. We will respond to reasonable requests as soon as practicable and as required by law. +49 2173 380. not subject to any local requirements that prohibit or restrict them from doing so. Zhao R, Chinai JM, Buhl S, et al. Leverkusen, ESG Ratings and The investment portfolio includes more than 50 companies. The financing will be used to advance NextPoints two lead precision immuno-oncology programs into the clinic, both targeting the newly discovered HHLA2 pathway to activate anti-tumor immune responses. Before using our Site, please inform yourself about Googles privacy policy (Link:http://www.google.com/privacy.html). Cookies, as well as other tracking technologies, such as HTML5 local storage, and Local Shared Objects (such as Flash cookies), and similar mechanisms, may record information such as a unique identifier, information you enter in a form, IP address, and other categories of data. About NextPoint Therapeutics NextPoint is advancing the field of immuno-oncology through its leading scientific work on the novel HHLA2 pathway. As permitted by law, certain data elements may not be subject to access, modification, portability, restriction, and/or deletion. Report, Quarterly NextPoint Therapeutics, founded and funded by MPM Capital, has assembled a team of proven drug developers to build a broad strategic pipeline of first-in-class #immunotherapies based on a novel,. in the United States absent registration or an applicable exemption from the registration Where we are processing your Personal Data, subject to applicable law, you also have the right to: To exercise your rights, you may contact us as atinfo@nextpointtx.com. 10+ years of pharmaceutical or biotechnology industry experience or mix of industry and academic experience in oncology or cancer immunotherapy with an emphasis on translational research, clinical biomarkers, and monoclonal antibodies, Proven track record of transitioning biomarkers from the bench to the clinic, Strong knowledge of immuno-oncology and associated biomarker approaches, Technical expertise in IHC, RNAscope, flow cytometry, genetics (including ctDNA), RNA-Seq, NanoString, qPCR and ELISAs, Proven success with filing INDs and supporting clinical trials, Competency with bioinformatic datasets and experience collaborating with bioinformaticians to analyze publicly available datasets, Excellent communication and interpersonal skills, personal integrity, professional manner, and ability to gain respect and develop good working relationships with cross functional personnel at all levels, Ability to balance multiple stakeholders and projects simultaneously, and able to operate with high accountability and under tight deadlines, Forward looking thinker, who actively seeks opportunities and proposes solutions with strong decision-making capability, A collaborator who communicates in an open, clear, complete, timely and consistent manner who listens effectively and invites response and discussion, Direct and run clinical operations and clinical trial launch activities for clinical programs, Manage clinical research organizations, clinical and testing lab vendors, Establish clinical operations infrastructure across the organization, Maintain relationships with Sites and KOLs, Represent NextPoint at Scientific and Investigator Meetings, Stay apprised of current trends in clinical trials research and regulatory landscape, Take responsibility for launch and day-to-day operational management of clinical trials including study sites, Participate in Clinical Vendor Governance and Safety Review Committee Meetings, Design and perform ligand binding assays in multi-well formats to analyze novel antibody therapeutics, Develop and execute functional assays involving primary human immune cells, mammalian cell culture, and multi-color flow cytometry to screen novel antibody therapeutics in an immune-oncology setting, Work independently to design and conduct experiments, analyze, interpret, and communicate data in team meetings and to leadership, Support the laboratory organization and operations by maintaining lab equipment and managing reagent and supply inventories, Bachelors degree in cell/molecular biology, immunology, or cancer biology or equivalent field, 2 + years hands-on experience in drug discovery research preferably in an industry setting, Experience with cell-based functional immune assays such as MLR, immune cell activity assays, and cytokine release assays, Experience with multiparameter flow cytometry, Hands on experience with murine tumor models preferred, Excellent verbal and written communication skills with a demonstrated ability to work collaboratively and thrive in a team environment, Excellent interpersonal skills and willingness to learn a variety of new techniques and technologies; flexibility to adapt to rapidly changing priorities and deadlines. Conduct, Product Protection Products & Seeds, Supplier Drive the clinical biomarker function to identify indications, support patient stratification and to inform on mechanism of action; develop, qualify, and execute biomarker assays with the most appropriate technical platforms to advance and support immune-oncology therapeutics to the clinic. PLEASE READ THIS DOCUMENT CAREFULLY BEFORE YOU ACCESS OR USE THE WEBSITE OR CONTENT. The securities referred to herein will not be registered under the U.S. Securities Act of 1933, as NextPoints approach re-activates immune cells in tumors that are suppressed by HHLA2-driven immune evasion. Bayer and the opportunities available. & Medical Devices, Crop Use the Website to artificially generate traffic or page links to a website or for any other purpose not expressly allowed under these Terms. shall form the basis of, or be relied upon in connection with, any offer or commitment and Social Needs, Bayer and The company offers immunotherapies for a validated checkpoint axis that is independent of PD-1/L1 and modulates both adaptive and innate immune systems to find and destroy cancer cells. R&D expenses before special items amounted to 5.3 billion euros. Please note that, subject to applicable law, we may continue to process your Personal Data even where you object if there are compelling legitimate grounds for processing that override your interests and rights, or where processing is necessary to establish, exercise, or defend legal claims. 2015 May 15;21(10):2359-66. access to the materials is prohibited or restricted. search, Main We may update this Privacy Notice from time to time. 51373 Leverkusen We are thrilled to support NextPoint, an exciting addition to our oncology portfolio, as it works to redefine the treatment landscape of immuno-oncology.. Lauren ArnoldMacDougall Advisors1(617)694-5387larnold@macdougall.bio, Programs target the novel HHLA2 pathway, activating anti-tumor immune responses to find and destroy cancer cells. In addition, you may contact the relevant data protection authority in the EU Member State of your residence, place of work or of the alleged infringement. 8+ years experience in a clinical operations role in biopharmaceutical industry with at least 5 years direct experience running oncology Ph1 clinical trials. Internet or other similar network activity information such as browsing history, login information, device type, accounts, IP address and other similar information concerning your interactions with our Site. This announcement is an advertisement and does not, under any circumstances, constitute a public We'd love to talk to you. Authority, Saudi Cancer Immunol Res. We encourage you to read the privacy policies of any Third-Party Site with which you choose to interact. Associate Director at Nextpoint Therapeutics Cambridge, Massachusetts, United States. in Pharmaceutical Science and Technology and I have a passion for medical affairs, pharmaceutical sciences, project management, and business development. NextPoint's programs aim to deliver monotherapies for cancer patients without viable treatment options. Learn more about Bayer and the opportunities available. prohibited or restricted. Among these areas are oncology, immunology, rare diseases, vaccines, potential cures in other core areas of Sanofis business footprint, and digital health solutions. About NextPoint Therapeutics NextPoint is advancing the field of immuno-oncology through its leading scientific work on the novel HHLA2 pathway. I have a keen interest in retail investing and enjoy long-distance running. These materials do not constitute or form a part of any offer or Experienced Management / Operations professional with a demonstrated history of working in the Biotech / Pharma industry and academic research. Germany on In the United Kingdom the following materials are only directed at (i) investment professionals Phone: +49 30 468 1111, Alfred-Nobel-Str. Health, Crop Our innovative approach integrates foundational. Transmit materials that contain any viruses, Trojan horses, worms, time bombs, cancelbots or other computer-programming routines that are intended to damage, detrimentally interfere with, surreptitiously intercept or expropriate any system, data or personal information. Global R&D, Events & Among these areas are oncology, immunology, rare diseases, vaccines, potential cures in other core areas of Sanofis business footprint, and digital health solutions. NextPoint Therapeutics, a biotechnology company developing a new world of precision immuno-oncology, announced today the appointment of Leena Gandhi, MD, PhD, as Chief Medical Officer (CMO).. As CMO, Dr. Gandhi will oversee the clinical development of NextPoint's precision immuno-oncology programs that target the newly discovered HHLA2 pathway to activate anti-tumor immune responses. A spokesperson for Boston-based NextPoint declined . Management, Bayer Previous study start-up and clinical monitoring experience desired. Republic, Ireland, Republic We use technical and organizational security measures designed to secure and protect Personal Data. Proc Natl Acad Sci U S A. Similar to PD-L1, the tumor antigen HHLA2 is a member of the B7 receptor family, is highly expressed on certain hard-to-treat cancers, and drives avoidance of detection from the immune system. Among these areas are oncology, immunology, rare diseases, vaccines, potential cures in other core areas of Sanofis business footprint, and digital health solutions. NextPoint Therapeutics is an exciting early-stage Boston-area startup company working at the frontier of immuno-oncology. NextPoint Therapeutics, a biotechnology company developing a new world of precision immuno-oncology, announced today that it raised $80 million in Series B financing co-led by Leaps by Bayer, the . Management, Supervisory The securities are only available to, and any invitation, Audio, electronic, visual, thermal, olfactory or similar information, We generally do not collect this type of information, Inferences drawn from other Personal Information. sufficient information on the terms of the offer and any securities to be offered so as to enable an offer within the meaning of Regulation (EU) 2017/1129. 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Most browsers allow you to control cookies, including whether or not to accept them, and how to remove them. & Rewards, Values Find out more: www.sanofiventures.com, Kira PeikoffLeaps by Bayer1(973)791-3348kira.peikoff@bayer.com. For purposes of this Privacy Notice, Personal Data means any information relating to an identified or identifiable natural person. By clicking on the I AGREE button, I certify that I am not located in the United States, Republic, Dominican There will be no public offer of the securities in any Phone: About BayerBayer is a global enterprise with core competencies in the life science fields of health care and nutrition. For purposes of this section, Personal Information means information that identifies, relates to, describes, is reasonably capable of being associate with, or could reasonably be linked, directly or indirectly, with you or your household. R&D expenses before special items amounted to 5.3 billion euros. In addition to the rights listed below, you have the right to not be discriminated against for exercising your rights. an offer to the public of the securities has not been made and will not be made in such Relevant Protection, Health and I am thrilled about Leaps by Bayer's investment in NextPoint Therapeutics, Inc., a company developing next-gen precision immuno-oncology therapies for patients Juergen Eckhardt auf LinkedIn: NextPoint Therapeutics Announces $80 Million Series B Financing co-led by And here is our regular feature in which we highlight a different person each week. Australia, Canada, South Africa or Japan or any other jurisdiction, where access to the materials is of, Palestinian Any person who is not a relevant person should not act or rely on the The investment portfolio includes more than 50 companies. 2021 Feb;9(2):156-169. Report, More expression Prospectus Directive includes any relevant implementing measure in each Relevant Member NextPoint is advancing the field of immuno-oncology through its leading scientific work on the novel HHLA2 pathway. Leaps by Bayer, a unit of Bayer AG, leads impact investments into solutions to some of todays biggest challenges in health and agriculture. of If you want to block the use and saving of cookies from the Site on to the computers hard drive, you should take the necessary steps within your web browsers settings to block all cookies from the Site and its external serving vendors, or use the cookie control system, if available upon first visit. Bayer is an innovation company with a more than 150-year history. This announcement is an advertisement and does not, under any NextPoint Therapeutics is an exciting early-stage Boston-area startup company working at the frontier of immuno-oncology. In other jurisdictions, only certain categories of person may be allowed to view such transaction not subject to, the registration requirements of the Securities Act. and Life in balance, Healthy Consulting, Our in the United States absent registration or an applicable exemption from the registration Development Policy, Corporate Life & Challenges, Reputation NextPoints approach re-activates immune cells in tumors that are suppressed by HHLA2-driven immune evasion. With our distinctive knowledge of people, animals and plants, You can use our locations menu to find Bayer country websites and NextPoint originated from the combined expertise of its academic founders, Gordon Freeman, PhD, of the Dana-Farber Cancer Institute, and XingXing Zang, PhD, of Albert Einstein College of Medicine. Secret of the Bridge, Rice Submit material that is intentionally false, defamatory, unlawfully threatening or unlawfully harassing. 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