Madrid, Spain, Recipharm Monts If you get the Moderna COVID-19 vaccine, there is a small chance that you could develop a skin reaction. headache, muscle pain, joint pain. Please include "Moderna COVID-19 Vaccine EUA" or "Moderna COVID-19 Vaccine, Bivalent EUA", as appropriate, in the first line of box #18 of the report form. The term "COVID arm" has been coined to describe a harmless delayed hypersensitivity reaction occurring approximately a week after administration of the novel SARS-CoV-2 mRNA vaccine. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. You can change your cookie settings at any time. Spikevax stimulates the bodys natural defences (immune system). Is the COVID Vaccine Safe for People With Lung Cancer? Erythromelalgia occurred after 5.9% of second doses, and cosmetic filler reactions occurred after 4.9% of second doses. All patients underwent serologic testing for SARS-CoV-2 infection before vaccination and tested negative, indicating no previous primary infection: hence, vasculitis might have been triggered by maladaptive individual immune responses to a component of the vaccine. Frequency of the most common manifestations of local injection-site reactions, by dose, were swelling (18% and 15%), erythema (18% and 20%), and pain (24% and 18%). The preferred site is the deltoid muscle of the upper arm. Spikevax can be given during breastfeeding. Registry participants collected information on the type and timing of vaccine doses and the morphology, timing, duration, and treatment of reactions. 2023 Feb 20:1-4. doi: 10.1007/s13691-023-00598-7. Careers. During and after each injection of the vaccine, your doctor, pharmacist or nurse will watch over you Do not use this vaccine after the expiry date which is stated on the label after EXP. Unable to load your collection due to an error, Unable to load your delegates due to an error. Less commonly, patients had episodes of zoster (shingles), herpes simplex flares, and rosacea-like reactions. A 5 mm skin punch biopsy was performed in patient 3, which showed only a mild lymphocytic perivascular infiltrate (. Federal government websites often end in .gov or .mil. Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. 2023 eHealthMe.com. "We have been involved with following skin reactions to COVID-19 vaccines, but the paper is pretty novel in that it covers a whole range of reactions that had not been reported from vaccine clinical trials," registry principal investigator Esther Freeman, MD, PhD, of Massachusetts General Hospital in Boston, told MedPage Today. From April, another bivalent COVID-19 vaccine will be available after the Australian Technical Advisory Group on Immunisation (ATAGI) approved Moderna's second Omicron-specific vaccine. There was also one person who had a delayed reaction after the second dose only. In most cases, the rash arose more than 24 hours after dosing (4.8% after the first dose, 4.9% after the second). No other type of reaction occurred in more than 1%-2% of patients after either dose. Moderna COVID Vaccine and Cellulitis staphylococcal - a phase IV clinical study of CDC and FDA data Summary: Cellulitis staphylococcal is reported only by a few people who get Moderna COVID Vaccine. Spikevax is is a white to off white dispersion supplied in a glass vial with a rubber stopper and aluminium seal. As the Times notes, not only did Moderna make roughly $36 billion in sales from COVID-19 vaccines worldwide, the company also received $10 billion in taxpayer funding to help develop and test the . Another report published in the Journal of the American Medical Association (JAMA) Dermatology on May 12, 2021 described 15 cases of skin reactionssometimes called "COVID arm"that occurred within two to 12 days after a first dose of the Moderna vaccine. We have a lot of things that are delayed hypersensitivity, like eczema, contact dermatitis, common antibiotic rashes," Blumenthal says. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Dermatopathology (Basel). Spikevax will be given to you as two 0.25 mL injections. Moderna COVID-19 vaccine generates long-lasting immune memory At a Glance People who received low doses of the Moderna COVID-19 vaccine had strong immune memories of the virus six months after being fully vaccinated. Interleukin 1alpha: a comprehensive review on the role of IL-1alpha in the pathogenesis and treatment of autoimmune and inflammatory diseases. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. lead to localised cellulitis, granuloma formation and abscess. Cellulitis staphylococcal in Pfizer BioNTech COVID Vaccine, Cellulitis staphylococcal in Johnson & Johnson COVID Vaccine, Abortion spontaneous (naturally occurring miscarriage), Acute myocardial infarction (acute heart attack), Ageusia (loss of taste functions of the tongue), Agitation (state of anxiety or nervous excitement), Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death), Angioedema (rapid swelling of the dermis), Appendicitis (inflammation of the appendix), Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat), Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires), Arthritis (form of joint disorder that involves inflammation of one or more joints), Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem), Atelectasis (partial or complete collapse of the lung), Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles), Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue), Belching (release of gas from the digestive tract), Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure), Blood thyroid stimulating hormone decreased, Bradycardia (abnormally slow heart action), Breast lump (localized swelling that feels different from the surrounding breast tissue), Bronchitis (inflammation of the mucous membrane in the bronchial tubes), Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder), Canker sores (painful, open sore in the mouth), Cardiomyopathy (weakening of the heart muscle), Cardio-respiratory arrest (sudden dysfunction of heart and lungs), Cerebral haemorrhage (bleeding within the brain), Cerebral infarction (less blood supply to brain resulting tissue damage), Chapped lips (cracking, fissuring, and peeling of the skin f lip), Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe), Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving), Concussion (short loss of normal brain function in response to a head injury), Coronary heart disease (narrowing or blockage of the coronary arteries), Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis), Dehydration (dryness resulting from the removal of water), Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it), Dermatitis allergic (inflammation of the skin due allergic reaction), Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens), Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall), Dyskinesia (abnormality or impairment of voluntary movement), Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear), Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters), Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat), Ejection fraction decreased (systolic heart failure), Encephalopathy (functioning of the brain is affected by some agent or condition), Erythema multiforme (a type of hypersensitivity reaction), Euphoric mood (excessively happy but may become angry or irritable), Eyelid ptosis (falling of the upper or lower eyelid), Eyelid twitch (spontaneous and uncontrolled spasms of the muscles), Facial paralysis (loss of function of face muscle), Facial paresis (weakness in facial muscle movement), Fainting (loss of consciousness and postural tone), Feeding disorder (when children refuse to eat certain food groups), Fibromyalgia (a long-term condition which causes pain all over the body), Flank pain (a distressing sensation experienced around the lower back and the upper abdomen), Flatulence (flatus expelled through the anus), Fluid retention (an abnormal accumulation of fluid in the blood), Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin), Gallstones (stone formation by bile component), Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus), Gastrointestinal disorder (functional problems of gastrointestinal tract), Gastrointestinal haemorrhage (bleeding gastrointestinal tract), General physical health deterioration (weak health status), Glossodynia (a burning or painful sensation in the tongue), Gout (uric acid crystals building up in the body), Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system), Haematochezia (passage of stools containing blood), Haematoma (collection of blood outside the blood vessels), Hallucinations (sensations that appear real but are created by your mind), Heart palpitations (feelings or sensations that your heart is pounding or racing), Hemiparesis (weakness on one side of the body), Hemiplegia (paralysis of one side of the body), Herpes simplex (herpes simplex is a common viral infection), Hyperacusis (disorder in loudness perception), Hyperhidrosis (abnormally increased sweating), Hyperkalemia (damage to or disease of the kidney), Hypoaesthesia (reduced sense of touch or sensation), Hypoaesthesia oral (reduced sense of touch or sensation in mouth), Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration), Hypotension (abnormally low blood pressure), Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development), Idiopathic or primary livedo reticularis (netlike pattern of reddish-blue skin discoloration, usually on the legs), Incoherent (talking in a confused and unclear way), Incontinence (lack of moderation or self-control), Injection site cellulitis (injection site inflammation), Injection site erythema (redness at injection site), Injection site haemorrhage (bleeding from injection site), Injection site nodule (small swelling or aggregation of cells in the body, esp. While the coronavirus 2019 (COVID-19) vaccine is currently being rolled out, some vaccine recipients are experiencing adverse effects (AEs), one of which includes a delayed large local reaction. Opens in a new tab or window, Share on Twitter. Epub 2020 Jul 23. 2021 Sep;20(9):2684-2690. doi: 10.1111/jocd.14312. Unable to load your collection due to an error, Unable to load your delegates due to an error. National Library of Medicine It will take only 2 minutes to fill in. The vaccine comes ready to use once thawed. eCollection 2022 Sep. Rodrguez Y, Rojas M, Beltrn S, Polo F, Camacho-Domnguez L, Morales SD, Gershwin ME, Anaya JM. Hosseinzadeh A, Ebrahimi K, Shahriarirad R, Dalfardi F. Clin Case Rep. 2022 Dec 15;10(12):e6317. If you miss a scheduled injection, you may not be fully protected against COVID-19. Breast Cancer and the COVID-19 Vaccine: Is It Safe? The authors explained that the small sample size limited their ability to identify any differences in the appearance of the reaction between races and ethnicities. Thromethamine Opens in a new tab or window, Visit us on Twitter. If you are concerned about a side-effect it can be reported directly via the Coronavirus Yellow Card reporting site or search for MHRA Yellow Card in the Google Play or Apple App Store and include the vaccine brand and batch/Lot number if available. Spikevax should be administered as two 0.25 mL (50 microgram) doses for children 6 through 11 years of age. Online ahead of print. MeSH COVID-19 vaccine benefits What are the benefits of getting a COVID-19 vaccine? The company has forecast Covid vaccine sales of $5 billion for . As of Sept 23, 2021, more than 83 million vaccine doses were administered in Italy, with approximately a fifth of recipients receiving ChAdOx1 nCoV-19 vaccine. How well it works: Moderna's initial Phase 3 clinical data in December 2020 was similar to Pfizer-BioNTech'sat that point, both vaccines showed about 95% efficacy for prevention of COVID-19. Moderna Inc will make certain contingent development, commercial and regulatory milestone payments to the U.S. National Institutes of Health (NIH) related to the development of COVID-19 vaccines . If you have any further questions, ask your doctor, pharmacist or nurse. A few cases of capillary leak syndrome flare-ups (causing fluid leakage from small blood vessels (capillaries) resulting in rapid swelling of the arms and legs, sudden weight gain and feeling faint, low blood pressure) have been reported following vaccination with Spikevax. 2021 Apr 13;22(1):276. doi: 10.1186/s13063-021-05180-1. This will help to protect you against COVID-19. 2020 Dec 1;16(12):2891-2904. doi: 10.1080/21645515.2020.1788310. This vaccine contains polyethylene glycol/macrogol (PEG) as part of PEG2000-DMG. To update your cookie settings, please visit the Cookie Preference Center for this site. Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years experience in consumer-oriented health and wellness content. Perspective of patients with autoimmune diseases on COVID-19 vaccination. Subcutaneous injection can happen inadvertently ( figure 1 ), affecting efficacy of vaccination and potentiate local adverse events. [A red and swollen arm after vaccination for covid-19]. Local injection-site reactions occurred after 24% and 25% of first and second doses, respectively. There are no data to assess the concomitant administration of Spikevax with other vaccines. -, Belouzard S, Millet JK, Licitra BN, Whittaker GR. Can People With MS Get the COVID-19 Vaccine? The rest of this document, including information about storage and handling, can be found in the PDF. Opens in a new tab or window, Visit us on LinkedIn. * Approximation only. doi: 10.1002/ccr3.6317. News. N Engl J Med. Spikevax will be given to you as two 0.5 mL injections. "It basically covered my whole shoulder," she said. 1 Local reactions include mild to moderate pain at the injection site, and systemic side effects like fatigue, headache, and fever have been common after Common Moderna COVID-19 Vaccine side effects may include: fever, chills; redness or a hardness and swelling where the shot was given; swelling or tenderness under your arm; nausea, vomiting; feeling tired; or. All rights reserved. Subcuta-neous injection can happen inadvertently (figure 1), affecting efficacy of vaccination and potentiate local adverse events. Trials. Epub 2022 Jun 21. They also stress that concerns about a skin reaction should not keep people from getting vaccinated. doi: 10.1093/ofid/ofac499. Epub 2021 Jul 1. Painful, pruritic, indurated, erythematous plaque, Painful, pruritic, indurated, erythematous plaque with minute papules inferior to ecchymoses at the, Sixty-year-old woman (patient 1) 24 h after initiation of topical steroid treatment; the, Pruritic, painful, erythematous, indurated plaque, Pruritic, painful, erythematous, indurated plaque at vaccine site in a 44-year-old woman (patient, Erythematous, pruritic, painful, indurated plaque, Erythematous, pruritic, painful, indurated plaque in a 33-year-old woman (patient 3) 7 days, MeSH Thank you, {{form.email}}, for signing up. doses of 0.25 mL can be delivered. 2023 Jan 6;23(1):7. doi: 10.1186/s12879-022-07973-4. Information about both vaccine doses was available for 180 patients, 29 of whom had skin reactions after both doses. If you are pregnant or think you may be pregnant, tell your doctor, nurse or pharmacist before you receive this vaccine. San Sebastin de los Reyes Spikevax may affect the way other medicines work, and other medicines may affect how Spikevax works. For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder. Four vaccines are approved by the European Medicines Agency: two messenger RNA-based vaccines encoding the spike protein of SARS-CoV-2 (BNT162b2, PfizerBioNTech; mRNA-1273, Moderna) and two adenoviral vector-basedvaccines encoding the spike protein (ChAdOx1 nCoV-19, AstraZeneca; Ad.26.COV2.S, Janssen). Key Points. Vaccines against SARS-CoV-2 represent a pivotal and effective countermeasure to contain the COVID-19 pandemic. A booster dose (0.25 mL) of Spikevax may be given at least 3 months after the second dose in News stories, speeches, letters and notices. 2021;12:215013272110244. doi:10.1177/21501327211024431, Baden L, El Sahly H, Essink B, et al. Ned Tijdschr Geneeskd. The Moderna Covid-19 vaccine is causing a small percentage of people to develop patches of inflamed skin and rashes around the injection site, up to 11 days after vaccination. Thromboses and COVID-19: reducing inflammation in addition to thromboprophylaxis. He joined MedPage Today in 2007. If you have itching, swelling, or tenderness at the injection site in the days after getting either dose of the vaccine, don't panic. government site. Read all of this leaflet carefully before you receive this vaccine because it contains important information for you. A new COVID-19 vaccine from Moderna targeting Omicron variants BA.4 and BA.5 will land in April. Covid Vaccination Linked to 21% Average Increase in a Large Number of Medical Problems. It is created by eHealthMe based on reports of 392,577 people who have side effects while getting Moderna COVID Vaccine from the CDC and the FDA, and is updated regularly. The initial report was limited to skin reactions associated with the Moderna and Pfizer vaccines, the only two with EUAs at the time of data analysis. Follow the COVID-19 vaccination schedule (below) based on age and medical condition. Dissecting cellulitis . The centre will offer NHS patients access to Moderna's COVID-19 vaccines that can protect against multiple variants. Bookshelf The recipient's health condition or recommendations for vaccination may change from one visit to the next. "Understandably, the clinical trials were focused on their major endpoints and didn't really provide a lot of detail on the skin reactions seen in patients.". While experiencing a reaction to a new vaccine can be frightening, Moderna only "reported delayed skin reactions in its large clinical trial in 0.8 percent of recipients after the first dose,. 2021 Elsevier Ltd. All rights reserved. Delayed large local reactions occurred after 15% of first doses and after 18% of second doses. Accessed April 28, 2021. and transmitted securely. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The reactions were first observed during a phase 3 clinical trial of the Moderna vaccine. The vaccine was also effective in people aged 65 years and in adolescents aged 12 to 17 years. Cutaneous adverse reactions following COVID-19 vaccinations: A systematic review and meta-analysis. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. PMC Rebecca Saff, MD, PhD, another lead author of the NEJM report and allergy fellowship director of the allergy and clinical immunology unit in the division of rheumatology, allergy, and immunology at Massachusetts General Hospital, tells Verywell that in the trial, "adverse events, including local adverse symptoms, were solicited for the seven days after the vaccine was given and unsolicited for 28 days after the vaccine, meaning that many of the more mild reactions may have been missed if they were after day seven.". SARS-CoV-2 infection has resulted in more than 4 million deaths worldwide, often due to excessive or aberrant host immune responses. Before Would you like email updates of new search results? doi: 10.1002/ccr3.6314. Accessibility 1 Injection site pain, redness, or swelling Both the Moderna vaccine and the Pfizer vaccine may produce a reaction around the area on your arm where you got your shot. The Lancet Regional Health Southeast Asia, The Lancet Regional Health Western Pacific, B cells: more than just for antibodies in SARS-CoV-2 vaccine responses, Haemophagocytic lymphohistiocytosis secondary to COVID-19: a case series, We use cookies to help provide and enhance our service and tailor content and ads. JAMA Dermatol. Keywords: Reasons Behind Breast Pain After the COVID-19 Vaccine, Psoriasis and COVID-19 Vaccine: What to Know. The https:// ensures that you are connecting to the COVID-19 vasculitis and novel vasculitis mimics. National Library of Medicine PMC COVID vaccines are essential to beat the virus - but they can cause side effects after having the jab. You can also apply ice for swelling and pain at the site of the shot. They vary in appearance and size and can sometimes cover most of the upper arm. The study was also limited to a single medical center during a short period of time. Tel: 0800 085 7562. We therefore aimed to evaluate humoral and cellular immune responses to COVID-19 vaccine BNT162b2 . Disclaimer. Do not puncture the vial more than 20 times. The active substance in Spikevax is mRNA encoding the SARS-CoV-2 Spike protein. 6th ed. The https:// ensures that you are connecting to the Later data on real-world effectiveness for adults showed that the protection from the mRNA two-dose primary series wanes over time, but booster doses bring the immune system back to robust levels. COVID arm that appeared in the contralateral upper extremity after mRNA-1273 booster inoculation. We report 3 cases of COVID arm, 2 of which were mistaken for cellulitis. These types of vaccines use a harmless, weakened animal virus that contains the genetic code for a protein unique to COVID-19, usually the spike protein. Reply. mRNA (Nucleoside-modified mRNA encoding the viral spike (S) glycoprotein of SARS-CoV-2; Lipids. . If you are immunocompromised, you may receive a third dose (0.5 mL for individuals 12 years of age and older; 0.25 mL for children 6 through 11 years) of Spikevax at least 1 month after the second dose. Thawed vials and filled syringes can be handled in room light conditions. Following vaccination, you should be alert to signs of myocarditis and pericarditis, such as breathlessness, palpitations and chest pain, and seek immediate medical attention should these occur. Before According to the FDA,. Spikevax should be administered by a trained healthcare professional. Eight days after getting injected with Moderna's Covid-19 vaccine, Hoang noticed her arm felt itchy. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Since the launch of their covid-19 vaccines, Moderna and Pfizer have accumulated more than $100bn (83; 94) in global revenues from salesmore than 20 times the World Health Organization's biennial budget in 2020-21.1 2 3 Yet for a vaccine that is estimated to cost $1-3 per dose to manufacture, both Moderna and Pfizer have announced plans to charge more than $110 a dose in the US this . "There may be genetic factors at playwe know that genetics can be a risk for certain T-cell reactions to drugsbut otherwise, we dont fully understand why someone has a response while another does [not] for most drugs and vaccines.". Careers. Subcutaneous injections can lead to localised cellulitis, granuloma formation and abscess. It appears as a red, warm, pruritic, indurated, or swollen area in the vicinity of the vaccine site. . Viruses. Q:. 2021;157(8):1000. doi:10.1001/jamadermatol.2021.2114. Meo SA, Bukhari IA, Akram J, Meo AS, Klonoff DC. Ask your pharmacist how to throw away medicines you no longer use. COVID-19 Resource Centre If you do develop one, don't panic. Cardiovascular symptoms, including faintness, syncope, altered mental status, palpitations, and hypotension. The COVID-19 vaccine has shown to have high efficacy if given correctly intramuscularly. Unlike cellulitis that tends to progress, or worsen over time, symptoms of skin reactions to COVID-19 vaccines tend to not progress, according a few case reports of vaccine reactions misdiagnosed as cellulitis that were published in the Journal of Primary Care & Community Health. Among those who received the Moderna vaccine, delayed large local skin reactions were most common, occurring in 175 of 267 (66%) patients after the first dose and 31 of 102 (30%) after the second dose. Most side effects go away within a few days of appearing. Spikevax is not recommended for children aged under 6 years. Very large clinical trials have shown that Moderna is effective in preventing COVID-19 in people aged 12 years and older. Having a skin reaction after the first shot does not mean you will have another reaction after another dose. Epub 2022 Aug 1. Spikevax is also available as two adapted . Reactions to the Moderna COVID-19 vaccine usually happen within 4 hours of injection. In order to improve the traceability of biological medicinal products, the name and the batch number of the administered product should be clearly recorded. HHS Vulnerability Disclosure, Help Spikevax is a vaccine used to prevent COVID-19 caused by SARS-CoV-2. Getting COVID-19 can cause all manner of odd skin reactions. Disclaimer. Lower limb lymphedema and cellulitis as a complication of COVID-19 vaccine: A case report. feeling faint or light-headed changes in your heartbeat shortness of breath wheezing swelling of your lips, face, tongue or throat hives or rash nausea or vomiting stomach pain Talk to your doctor. Studies suggest that delayed skin reactions occurring days or a week after the shot may affect fewer than one in 100 people. Worry over having a skin reaction should not deter you from getting a COVID-19 vaccine. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Epub 2022 Aug 24. Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine: supplementary appendix. Clinicians can distinguish SARS-CoV-2 vaccine reactions from cellulitis by the time of onset (approximately a week vs 5 days), by the lack of progression of symptoms, and resolution over 4 to 5 days. Severe cases of COVID arm may be treated with topical steroids. Caroline Tien is a journalist with degrees in English and biology. A few patients developed pernio/chilblains, better known as "COVID toes." To relieve symptoms, experts recommend taking an antihistamine and using a topical steroids for any itchiness, swelling, and redness. 2022 Jan;33 Suppl 27(Suppl 27):58-60. doi: 10.1111/pai.13631. Spikevax uses a substance called messenger ribonucleic acid (mRNA) to carry instructions that cells in the body can use to make the spike protein that is also on the virus. The .gov means its official. The swelling typically goes down in about two to 11 days. As Spikevax does not contain the virus, it cannot give you COVID-19. 20052022 MedPage Today, LLC, a Ziff Davis company. Government activity Departments. They have been observed more often after the second dose compared to the first dose, and more often in younger males. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. The phase IV clinical study analyzes which people get Moderna COVID Vaccine and have Cellulitis staphylococcal. It is given to adults and children aged 6 years and older. There was also someone whose reaction was mistaken for cellulitis and treated with antibiotics noted in the JAMA Dermatology report of patients at Yale New Haven Hospital.
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